THIS PAGE IS INTENDED FOR UK PATIENTS WHO HAVE BEEN PRESCRIBED STALADEX® (leuprorelin acetate)
Adverse event reporting can be found at the bottom of the page.
Staladex® (leuproelin acetate)
What is Staladex? 1,2
Staladex is a treatment that helps reduce the level of the male hormone, testosterone. This hormone plays a role in the growth of prostate cancer cells.
Staladex is used to treat adult men with prostate cancer.*
How does Staladex work? 1,2
Staladex is an implant that contains an active ingredient called leuprorelin. This belongs to a group of medicines called luteinising hormone-releasing hormone (LHRH) agonists.
Staladex works by reducing the level of testosterone by blocking the production of luteinising hormone (LH) in the body, a key hormone that helps produce testosterone.
How is Staladex administered? 1,2
Staladex is injected under the skin of your stomach. This will be given by a doctor or nurse either at a hospital or clinic.
How often do I have to take Staladex? 1,2
Staladex is a ready-to-use implant that should be administered once every 3 months. Be sure to remind your doctor or nurse to schedule your next injection.
If your next appointment is more or less than 3 months since your last dose, contact your doctor or nurse to ensure Staladex is administered correctly.
What happens if I miss a dose?
For Staladex to work effectively, it is important that you have your injections regularly as directed by your doctor.
If you are unable to attend an appointment for your injection contact your doctor, nurse or hospital as soon as possible to re-schedule.
Can I stop my treatment?
It is important to continue treatment with Staladex even if you feel well. Follow your treatment plan until your doctor advises that it is time to stop.
I was on a previous treatment similar to Staladex, is this any different? 1,2
Staladex is considered to work in the same way as your previous injectable medicine. Your doctor may have reviewed your treatment and decided on changing your treatment to Staladex. You will be given Staladex once every 3 months and should request repeat prescriptions in the same way.
What are the most common side effects? 1,2
Like all medications, Staladex can cause side effects. However, it is important to remember that not everybody gets them.
The most common side effects associated with LHRH agonists such as Staladex® (those which may affect more than 1 in 10 people) includes weight changes, hot flushes, sweating, muscle weakness, bone pain, changes to your sex life, a reduction in size and function of the testes, tiredness and skin reactions at the injection sites.≠
If you get any side effects, talk to your doctor, nurse or pharmacist. This includes any possible side effects not listed in the package leaflet.
Further Information
If you have any questions regarding your treatment or illness, do not hesitate to discuss these with your doctor or nurse.
Footnotes/Abbreviations
* Staladex is indicated in men with high risk localised, advanced and metastatic prostate cancer. Please seek further information from your doctor or nurse.
≠ For a full list of possible side effects, please read your patient information leaflet which comes with your Staladex implant. These side effects apply to all similar hormonal treatment for prostate cancer
References
References
1. Staladex SmPC
2. eMC. Staladex 11.25 mg patient information leaflet. https://www.medicines.org.uk/emc/files/pil.15547.pdf (Accessed March
2025).
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